Product Name :
Neoquassin
Description:
Neoquassine is a CYP1A1 inhibitor isolated from Picrasma excelsa. Neoquassin is found in Picrasma quassioides.
CAS:
76-77-7
Molecular Weight:
390.47
Formula:
C22H30O6
Chemical Name:
(1S, 2S, 6S, 7S, 9R, 13R, 17S)-11-hydroxy-4, 15-dimethoxy-2, 6, 14, 17-tetramethyl-10-oxatetracyclo[7.7.1.0, .0, ]heptadeca-4, 14-diene-3, 16-dione
Smiles :
CC1[C@@H]2CC(O)O[C@@H]3C[C@H]4[C@H](C)C=C(OC)C(=O)[C@]4(C)[C@@H](C(=O)C=1OC)[C@@]32C
InChiKey:
BDQNCUODBJZKIY-NUPPOKJBSA-N
InChi :
InChI=1S/C22H30O6/c1-10-7-14(26-5)20(25)22(4)12(10)8-15-21(3)13(9-16(23)28-15)11(2)18(27-6)17(24)19(21)22/h7,10,12-13,15-16,19,23H,8-9H2,1-6H3/t10-,12+,13+,15-,16?,19+,21-,22+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Aflibercept (VEGF Trap)} web|{Aflibercept (VEGF Trap)} Protein Tyrosine Kinase/RTK|{Aflibercept (VEGF Trap)} Biological Activity|{Aflibercept (VEGF Trap)} Description|{Aflibercept (VEGF Trap)} custom synthesis|{Aflibercept (VEGF Trap)} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.{{Fruquintinib} MedChemExpress|{Fruquintinib} Protein Tyrosine Kinase/RTK|{Fruquintinib} Technical Information|{Fruquintinib} In Vitro|{Fruquintinib} manufacturer|{Fruquintinib} Epigenetics}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Neoquassine is a CYP1A1 inhibitor isolated from Picrasma excelsa. Neoquassin is found in Picrasma quassioides.|Product information|CAS Number: 76-77-7|Molecular Weight: 390.47|Formula: C22H30O6|Chemical Name: (1S, 2S, 6S, 7S, 9R, 13R, 17S)-11-hydroxy-4, 15-dimethoxy-2, 6, 14, 17-tetramethyl-10-oxatetracyclo[7.7.1.0, .0, ]heptadeca-4, 14-diene-3, 16-dione|Smiles: CC1[C@@H]2CC(O)O[C@@H]3C[C@H]4[C@H](C)C=C(OC)C(=O)[C@]4(C)[C@@H](C(=O)C=1OC)[C@@]32C|InChiKey: BDQNCUODBJZKIY-NUPPOKJBSA-N|InChi: InChI=1S/C22H30O6/c1-10-7-14(26-5)20(25)22(4)12(10)8-15-21(3)13(9-16(23)28-15)11(2)18(27-6)17(24)19(21)22/h7,10,12-13,15-16,19,23H,8-9H2,1-6H3/t10-,12+,13+,15-,16?,19+,21-,22+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:25558565 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Mishra K, Chakraborty D, Pal A, Dey N. Plasmodium falciparum: in vitro interaction of quassin and neo-quassin with artesunate, a hemisuccinate derivative of artemisinin. Exp Parasitol. 2010 Apr;124(4):421-7. doi: 10.1016/j.exppara.2009.12.007. Epub 2009 Dec 29. PubMed PMID: 20036657.Lang’at-Thoruwa C, Kirby GC, Phillipson JD, Warhurst DC, Watt RA, Wright CW. Enhancement of the antiplasmodial activity of quassin by transformation into a gamma-lactone. J Nat Prod. 2003 Nov;66(11):1486-9. PubMed PMID: 14640524.Products are for research use only. Not for human use.|
