Product Name :
LSN2463359
Description:
LSN2463359 is positive allosteric modulator of metabotropic glutamate 5 (mGlu5). LSN2463359 attenuates aspects of the behavioral response to administration of the competitive NMDA receptor antagonist. LSN2463359 selectively attenuates reversal learning deficits observed in the neurodevelopmental MAM E17 model.
CAS:
1401031-52-4
Molecular Weight:
265.31
Formula:
C16H15N3O
Chemical Name:
Smiles :
CC(C)NC(=O)C1=CC=C(C=N1)C#CC1C=CN=CC=1
InChiKey:
STAFRSGTRKNXHF-UHFFFAOYSA-N
InChi :
InChI=1S/C16H15N3O/c1-12(2)19-16(20)15-6-5-14(11-18-15)4-3-13-7-9-17-10-8-13/h5-12H,1-2H3,(H,19,20)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{BODIPY 558/568 C12} MedChemExpress|{BODIPY 558/568 C12} {Fluorescent Dye}|{BODIPY 558/568 C12} Purity & Documentation|{BODIPY 558/568 C12} References|{BODIPY 558/568 C12} manufacturer|{BODIPY 558/568 C12} Autophagy}
Shelf Life:
≥12 months if stored properly.{{Retifanlimab} MedChemExpress|{Retifanlimab} PD-1/PD-L1|{Retifanlimab} Biological Activity|{Retifanlimab} Purity|{Retifanlimab} custom synthesis|{Retifanlimab} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32926338
Additional information:
LSN2463359 is positive allosteric modulator of metabotropic glutamate 5 (mGlu5). LSN2463359 attenuates aspects of the behavioral response to administration of the competitive NMDA receptor antagonist. LSN2463359 selectively attenuates reversal learning deficits observed in the neurodevelopmental MAM E17 model.|Product information|CAS Number: 1401031-52-4|Molecular Weight: 265.31|Formula: C16H15N3O|Smiles: CC(C)NC(=O)C1=CC=C(C=N1)C#CC1C=CN=CC=1|InChiKey: STAFRSGTRKNXHF-UHFFFAOYSA-N|InChi: InChI=1S/C16H15N3O/c1-12(2)19-16(20)15-6-5-14(11-18-15)4-3-13-7-9-17-10-8-13/h5-12H,1-2H3,(H,19,20)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Gastambide F, et al. The mGlu₅ positive allosteric modulator LSN2463359 differentially modulates motor, instrumental and cognitive effects of NMDA receptor antagonists in the rat. Neuropharmacology. 2013;64:240-247.Products are for research use only. Not for human use.|
