Product Name :
Gly-Arg-Gly-Asp-Ser
Description:
Gly-Arg-Gly-Asp-Ser is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin. Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC50 of ∼5 and ∼6.5 μM
CAS:
96426-21-0
Molecular Weight:
490.47
Formula:
C17H30N8O9
Chemical Name:
(3S)-3-{2-[(2S)-2-(2-aminoacetamido)-5-[(diaminomethylidene)amino]pentanamido]acetamido}-3-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}propanoic acid
Smiles :
NC(N)=NCCC[C@H](NC(=O)CN)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(O)=O
InChiKey:
RGNVSYKVCGAEHK-GUBZILKMSA-N
InChi :
InChI=1S/C17H30N8O9/c18-5-11(27)23-8(2-1-3-21-17(19)20)14(31)22-6-12(28)24-9(4-13(29)30)15(32)25-10(7-26)16(33)34/h8-10,26H,1-7,18H2,(H,22,31)(H,23,27)(H,24,28)(H,25,32)(H,29,30)(H,33,34)(H4,19,20,21)/t8-,9-,10-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Tezosentan} MedChemExpress|{Tezosentan} Endothelin Receptor|{Tezosentan} Epigenetics|{Tezosentan} Biological Activity|{Tezosentan} Description|{Tezosentan} supplier}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Gly-Arg-Gly-Asp-Ser is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin. Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC50 of ∼5 and ∼6.5 μM|Product information|CAS Number: 96426-21-0|Molecular Weight: 490.47|Formula: C17H30N8O9|Chemical Name: (3S)-3-{2-[(2S)-2-(2-aminoacetamido)-5-[(diaminomethylidene)amino]pentanamido]acetamido}-3-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}propanoic acid|Smiles: NC(N)=NCCC[C@H](NC(=O)CN)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(O)=O|InChiKey: RGNVSYKVCGAEHK-GUBZILKMSA-N|InChi: InChI=1S/C17H30N8O9/c18-5-11(27)23-8(2-1-3-21-17(19)20)14(31)22-6-12(28)24-9(4-13(29)30)15(32)25-10(7-26)16(33)34/h8-10,26H,1-7,18H2,(H,22,31)(H,23,27)(H,24,28)(H,25,32)(H,29,30)(H,33,34)(H4,19,20,21)/t8-,9-,10-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (203.{{Limantrafin} web|{Limantrafin} Stem Cell/Wnt|{Limantrafin} Activator|{Limantrafin} Purity & Documentation|{Limantrafin} Formula|{Limantrafin} manufacturer} 89 mM; Need ultrasonic).PMID:35116795 H2O : 33.33 mg/mL (67.96 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3, with IC50 of 5 μM. Gly-Arg-Gly-Asp-Ser-immobilized TiO2 nanotubes enhance osteoblast-like cell (MG-63) adhesion, and significantly increased cell spreading and proliferation.|Products are for research use only. Not for human use.|
