Nterests.Authors’ ContributionsJun Han, Hang-Hang Xu, Xiao-Long Chen, Hao-Ran Hu, and Kun-Mei Hu Performed the experiments and analyze data. Jun Han and Guo-Wei He wrote up the manuscript. Jun Han and Zhi-Wu Chen developed the protocol and discussion around the results. Guo-Wei He contributed to vital discussion on the study style, benefits, presentation, writing up, and submission.AcknowledgmentsThe authors appreciated the contributions from the other members of our laboratory: ZL QIN, H YU, FY FAN, and XW LI. This study was supported by the National Organic Science Foundation of China under Grant no. 81173596; the Natural Science Foundation in the Department of Education of Anhui province below Grant no. KJ2015A157. This study was supported by an unrestricted grant from Recordati SpA.AbbreviationACh: BCA: CIR: CBA: EDHF: EEG: GAPDH: IR: PGI2 : NO: PSS: RR: SD rats: TRP: TRPV: TFR: Acetylcholine Bicinchoninic acid Cerebral ischemia-reperfusion Cerebral basal artery Endothelium-dependent hyperpolarizing factor Electroencephalograph Glyceraldehyde 3-phosphate dehydrogenase Ischemia/reperfusion injury Prostacyclin Nitric oxide Precooled physiological salt remedy Ruthenium red Sprague-Dawley rats Transient receptor possible TRP vanilloid channel Total flavonoids of Rhododendron.
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