A20/TNFAIP3 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the C-terminus region of human A20. The exact sequence is proprietary.
|
| Localization |
Cytoplasm; Nucleus
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
TNFAIP3
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
90 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Mouse (83%), Porcine (81%), Rhesus Monkey (97%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.63 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for A20/TNFAIP3 Antibody
- A20
- A20TNFA1P2
- EC 3.4.19.12
- EC 6.3.2.-
- MGC104522
- MGC138687
- OTU domain-containing protein 7C
- OTUD7C
- OTUD7CMGC138688
- Putative DNA-binding protein A20
- TNF alpha-induced protein 3
- TNFA1P2
- TNFAIP3
- tumor necrosis factor alpha-induced protein 3
- tumor necrosis factor inducible protein A20
- tumor necrosis factor, alpha-induced protein 3
- Zinc finger protein A20
Background
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. Knockout studies of a similar gene in mice suggested that this gene is critical for limiting inflammation by terminating TNF-induced NF-kappa B responses. [provided by RefSeq]
