ABCG2/CD338 Antibody Summary
| Immunogen |
This antibody is specific for the N Terminus Region of the target protein.
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| Marker |
Stem Cell Marker
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| Specificity |
This product is specific for Human ABCG2.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
ABCG2
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody is useful in ELISA.
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| Publications |
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Reactivity Notes
Human.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
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| Preservative |
No Preservative
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| Purity |
Immunogen affinity purified
|
Notes
Manufactured by SDIXs proprietary Genomic Antibody Technology™. GAT FAQs.
Alternate Names for ABCG2/CD338 Antibody
- ABC transporter
- ABC15
- ABCG2
- ABCP
- ABCPMGC102821
- ATP-binding cassette sub-family G member 2
- ATP-binding cassette transporter G2
- ATP-binding cassette, sub-family G (WHITE), member 2
- BCRP
- BCRP1
- BCRPMRX
- BMDP
- Breast cancer resistance protein
- CD338 antigen
- CD338
- CDw338
- EST157481
- mitoxantrone resistance protein
- Mitoxantrone resistance-associated protein
- MXR
- MXRMXR1
- placenta specific MDR protein
- Placenta-specific ATP-binding cassette transporter
Background
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. [provided by RefSeq]
