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Product: ML RR-S2 CDA (ammonium salt)

AF10 Antibody (HAF10 10D3/8) Summary

Immunogen
Synthetic peptide: RLSDKTGPVAQEKS, corresponding to amino acids 1055-1069 of Human AF10.
Localization
Nuclear
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
MLLT10
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100 – 1:2000
  • ELISA 1:100 – 1:2000
  • Immunohistochemistry 1:10 – 1:500
  • Immunoprecipitation 1:10 – 1:500
Positive Control
AF10 Lysate (NBL1-13135)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A or G purified

Alternate Names for AF10 Antibody (HAF10 10D3/8)

  • AF10MGC75086
  • ALL1-fused gene from chromosome 10 protein
  • DKFZp686E10210
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog);translocated to, 10
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila);translocated to, 10
  • protein AF-10
  • type I AF10 protein

Background

AF10 is a putative transcription factor containing a leucine zipper motif. A t(10;11)(p12;q23) chromosomal translocation present in a proportion of acute myeloid leukaemias results in expression of an AF10 (carboxy terminus) MLL (amino terminus) fusion protein.

PMID: 16183055

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Author: premierroofingandsidinginc