Aurora C Antibody Summary
| Immunogen |
Peptide with sequence PRAVVQLGKAQP-C corresponding to N-Terminus according to NP_001015878.1.
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| Epitope |
PRAVVQLGKAQP-C
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| Specificity |
This antibody is expected to recognize isoform 1 (NP_001015878.1) only.
|
| Clonality |
Polyclonal
|
| Host |
Goat
|
| Gene |
AURKC
|
| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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|
| Application Notes |
WB: Approx. 36 kDa band observed in human testis lysates (calculated MW of 35.6 kDa band according to NP_001015878.1).
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
|
| Preservative |
0.02% Sodium Azide
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Aurora C Antibody
- AIE2AIK3
- ARK3Serine/threonine-protein kinase aurora-C
- AurC
- aurora kinase CAurora/IPL1/Eg2 protein 2
- Aurora/IPL1-related kinase 3
- aurora-C
- Aurora-related kinase 3
- EC 2.7.11
- EC 2.7.11.1
- serine/threonine kinase 13 (aurora/IPL1-like)
- serine/threonine-protein kinase 13
- STK13ARK-3
Background
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
