BLMH/Bleomycin Hydrolase Overexpression Lysate (Denatured) Summary
| Description |
Pasmid: pCMV-BLMH full-length
|
| Gene |
BLMH
|
Packaging, Storage & Formulations
| Storage |
Store at -80C. Avoid freeze-thaw cycles.
|
| Buffer |
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).
|
Lysate Details for BLMH/Bleomycin Hydrolase
| Type |
Overexpression
|
| Protein State |
Denatured
|
Notes
Quality control test: Transient overexpression cell lysate was tested with Anti-BLMH antibody by Western Blots.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for BLMH/Bleomycin Hydrolase Overexpression Lysate (Denatured)
- BHBMHBLM hydrolase
- bleomycin hydrolase
- BLMH
- BMH
- EC 3.4.22.40
Background
Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. [provided by RefSeq]
