CCR9 Antibody Summary
| Immunogen |
Synthetic 17 amino acid peptide from 2nd cytoplasmic domain of human CCR9.
|
| Localization |
Membrane; multi pass membrane protein.
|
| Specificity |
Human CCR9. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
CCR9
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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Reactivity Notes
Predicted cross-reactivitiy based on sequence identity: Gorilla (100%), Gibbon (100%), Marmost (88%), Bat (88%), Sheep (82%), Bovine (82%), Equine (82%), Porcine (82%), Opossum (82%).
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
|
| Preservative |
0.1% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for CCR9 Antibody
- C-C chemokine receptor type 9
- C-C CKR-9
- CC-CKR-9
- CCR9
- CCR-9
- CD199
- CDw199 antigen
- CDw199
- chemokine (C-C motif) receptor 9
- G protein-coupled receptor 28
- GPR28
- GPR-9-6G-protein coupled receptor 28
Background
CCR9, a chemokine receptor, is expressed in thymocytes and T lymphocytes from the small intestine and colon but not in lymphocytes from tonsils, lung, inflamed liver, normal or inflamed skin, inflamed synovium and synovial fluid, breast milk, and seminal fluid (Kunkel et al., 2000). CCR9 is not detected in natural killer cells, monocytes, eosinophils, basophils, and neutrophils. CCR9 binds TECK (thymus-expressed chemokine), a CC chemokine expressed in thymus and small intestine. TECK chemoattracts dendritic cells, thymocytes, and activated macrophages.
