CD31/PECAM-1 Antibody Summary
| Immunogen |
Synthetic peptide corresponding to C-terminus of mouse CD31 protein.
|
| Localization |
Membrane
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
PECAM1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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Reactivity Notes
Tested in Human. Predicted cross-reactivity based on sequence identity: Mouse, Pig
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
50mM Tris (pH 7.6) and 1.0% BSA
|
| Preservative |
0.1% Sodium Azide
|
| Concentration |
Predilute
|
| Purity |
Immunogen affinity purified
|
Alternate Names for CD31/PECAM-1 Antibody
- adhesion molecule
- CD31 antigen
- CD31
- CD31/EndoCAM
- endoCAM
- FLJ34100
- FLJ58394
- GPIIA
- PECA1
- PECAM1
- PECAM-1
- PECAM-1, CD31/EndoCAM
- platelet endothelial cell adhesion molecule
- platelet/endothelial cell adhesion molecule
Background
CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed on the surface of endothelial cells and is specifically concentrated at the junction between them. Therefore, CD31 antibodies are commonly used as endothelial markers to measure angiogenesis in association with tumor recurrence. It is also weakly expressed on many peripheral lymphoid cells and platelets. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas). It is also weakly expressed on many peripheral lymphoid cells and platelets.
