CENPJ Antibody Summary
| Immunogen |
The immunogen for this product maps to a region between residue 675 and 725 of human Centromere Protein J using the numbering given in entry NP_060921.2 (GeneID 55835).
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
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| Gene |
CENPJ
|
| Purity |
Immunogen affinity purified
|
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
TBS and 0.1% BSA
|
| Preservative |
0.09% Sodium Azide
|
| Concentration |
0.2 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for CENPJ Antibody
- BM032
- CENP-J
- centromere protein J
- Centrosomal P4.1-associated protein
- CPAPMCPH6
- LAG-3-associated protein
- LAPSCKL4
- LIP1microcephaly, primary autosomal recessive 6
- LYST-interacting protein 1
- LYST-interacting protein LIP1
- LYST-interacting protein LIP7
- MGC131581
- MGC131582
- MGC142222
- MGC142224
- Sas-4
- SASS4
Background
This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation.
