Product: Bromocriptine (mesylate)
CHD1L Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human CHD1L. The exact sequence is proprietary.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
CHD1L
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
1XPBS, 20% Glycerol (pH7)
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1.02 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for CHD1L Antibody
- ALC1
- amplified in liver cancer 1
- amplified in liver cancer protein 1
- CHD1L
- CHDL
- chromodomain helicase DNA binding protein 1-like
- chromodomain-helicase-DNA-binding protein 1-like
- FLJ22530
Background
In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1; MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).[supplied by OMIM]
