C-Peptide Antibody (2B7) Summary
| Immunogen |
Recombinant full length protein.
|
| Epitope |
The three-dimensional structure generated by N- and C- terminal regions of C-peptide separated by beta-turn at position 47-50 of proinsulin.
|
| Localization |
Secreted
|
| Specificity |
Affinity (Kd) > 1 x 10^8.Binds to the human free C-peptide and proinsulin molecules.No cross reactivity with human, bovine, porcine insulins.
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
INS
|
| Purity |
Protein A purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Competitive ELISA or RIA detection of C-peptide in human serum without or after immunospecific removal of proinsulin (with solid-phased ab8299 (1D6) to human proinsulin)Construction of a sensitive two-site sandwich EIA/ RIA immunosorbent assays for the measurement of total (including proinsulin convertion intermediates) human proinsulin in serum. ab8297 used in conjunction with this antibody would be suitable.Specific immunosorbtional (with solid-phase 2B7) removal of total proinsulin and C-peptide molecules from serum samples before the measurement of human insulin
|
Reactivity Notes
Cross-reacts with Human. Does not react with Bovine, Mouse, Rat or Pig
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
0.09% Sodium Azide
|
| Purity |
Protein A purified
|
Alternate Names for C-Peptide Antibody (2B7)
- C-P
- C-Peptide
- IDDM2
- ILPR
- Insulin C-Peptide
- insulin
- IRDN
- MODY10
- Proinsulin C-Peptide
- proinsulin
Background
This antibody detects human Insulin and a different epitope than the monoclonal, ab8297.
