Caveolin-1 Antibody Summary
Immunogen |
This antibody was made against a protein fragment from the N Terminus Region
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Marker |
Caveolae Marker, Endosome Marker
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Specificity |
This product is specific for Human CAV1.
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Clonality |
Polyclonal
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Host |
Rabbit
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Gene |
CAV1
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Purity |
Immunogen affinity purified
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Applications/Dilutions
Dilutions |
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Application Notes |
This antibody is useful in ELISA and Western Blot.
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Publications |
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Reactivity Notes
Human.
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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Buffer |
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
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Preservative |
No Preservative
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Purity |
Immunogen affinity purified
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Notes
Manufactured by SDIXs proprietary Genomic Antibody Technology. GAT FAQs. These products are available in limited quantities. Please enquire about the availability of this product before purchasing.
Alternate Names for Caveolin-1 Antibody
- CAV
- CAV1
- caveolae protein, 22kD
- caveolin 1, caveolae protein, 22kDa
- Caveolin1
- Caveolin-1
- cell growth-inhibiting protein 32
- MSTP085
- VIP21
Background
Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24 kDa integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types.