Cysteinyl Leukotriene R2/CysLTR2 Antibody Summary
| Immunogen |
Synthetic 17 amino acid peptide from 1st extracellular domain of human CYSLTR2 / CYSLT2.
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| Specificity |
Human CYSLTR2 / CYSLT2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR109B (59%), OXGR1 (59%), GPR81 (59%).
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| Predicted Species |
Monkey (94%), Primate (94%). Backed by our 100% Guarantee.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
CYSLTR2
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Gibbon (100%), Marmoset (100%), Gorilla (94%), Panda (94%), Canine (88%), Bovine (88%), Hamster (88%), Elephant (88%), Rabbit (88%), Opossum (88%), Porcine (88%).
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
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| Preservative |
0.1% Sodium Azide
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| Concentration |
1.0 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for Cysteinyl Leukotriene R2/CysLTR2 Antibody
- CysLT(2)
- CysLT2
- CYSLT2KPG_011
- CYSLT2RHG57
- CysLTR2
- cysteinyl leukotriene CysLT2 receptor
- Cysteinyl Leukotriene R2
- cysteinyl leukotriene receptor 2
- Cysteinyl LeukotrieneR2
- G protein-coupled receptor
- G-protein coupled receptor GPCR21
- G-protein coupled receptor HG57
- HG57
- hGPCR21
- HPN321
- KPG_011
Background
Cysteinyl leukotriene receptor 2 (CysLT2) is a Chemoattractant Receptor that binds neutrophil chemoattractants such as cysteinyl leukotrienes. These ligands have potent proinflammatory activity and are implicated in many features of asthma including edema, bronchial constriction, and hyperreactivity (Bisgaard et al., 2000). Activation of cysteinyl leukotriene receptor 2 induces cell contraction and/or relaxation.
