Product: Chondroitin (sulfate)
Cytochrome P450 2C8 Antibody Summary
| Immunogen |
Peptide with sequence C-KNVALTRSYIREK corresponding to internal region according to NP_000761.3, NP_001185782.1, NP_001185783.1.
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| Specificity |
This antibody is expected to recognize all reported isoforms (NP_000761.3; NP_001185782.1; NP_001185783.1). No cross-reactivity with other 2C proteins expected. Reported variants represent identical protein: NP_001185782.1, NP_001185784.1
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
CYP2C8
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Approx. 55 kDa band observed in human liver lysates (calculated MW of 55.8 kDa band according to NP_000761.3).
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
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| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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| Preservative |
0.02% Sodium Azide
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| Concentration |
0.5 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for Cytochrome P450 2C8 Antibody
- CPC8
- CYPIIC8
- cytochrome P450 2C8
- Cytochrome P450 form 1
- Cytochrome P450 IIC2
- Cytochrome P450 MP-12
- Cytochrome P450 MP-20
- cytochrome P450, family 2, subfamily C, polypeptide 8
- cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8
- EC 1.14.14.1
- flavoprotein-linked monooxygenase
- microsomal monooxygenase
- MP-12/MP-20
- P450 form 1
- S-mephenytoin 4-hydroxylase
- xenobiotic monooxygenase
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.
