DC-SIGNR/CD299/CLEC4M Antibody (16E7) [DyLight 405] Summary
| Additional Information |
Recombinant Monoclonal Antibody
|
| Immunogen |
CD299
|
| Specificity |
Human CD299, which is an oligomeric type II transmembrane protein with a C-type lectin extracellular domain, the expression of which is restricted to immature DC, macrophages in the lung, and endothelial cells in the liver. It binds ICAM-3 and ICAM-7 to mediate the interaction of DC with T lymphocytes and endothelial cells in the initial stages of immune response and in the migratory behavior of DC. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection.
|
| Isotype |
IgG
|
| Clonality |
Monoclonal
|
| Host |
Rabbit
|
| Gene |
CLEC4M
|
| Purity |
Protein A or G purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Optimal dilution of this antibody should be experimentally determined.
|
Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark.
|
| Buffer |
50mM Sodium Borate
|
| Preservative |
0.05% Sodium Azide
|
| Purity |
Protein A or G purified
|
Notes
Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for DC-SIGNR/CD299/CLEC4M Antibody (16E7) [DyLight 405]
- CD209L
- CD209L1
- CD209Ldendritic cell-specific ICAM-3-grabbing nonintegrin 2
- CD299 antigenMGC129964
- CD299
- CLEC4M
- C-type lectin domain family 4, member M
- DC-SIGN2
- DC-SIGN2CD209 antigen-like protein 1
- DCSIGNR
- DC-SIGNR
- DC-SIGNRDC-SIGN-related protein
- DCSIGNRMGC47866
- Dendritic cell-specific ICAM-3-grabbing non-integrin 2
- HP10347
- liver/lymph node-specific ICAM-3 grabbing non-integrin
- Liver/lymph node-specific ICAM-3-grabbing non-integrin
- LSIGN
- L-SIGN
- LSIGNC-type lectin domain family 4 member M
- mannose binding C-type lectin DC-SIGNR
