DDX50 Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to a region between residue 687 and 737 of human DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 using the numbering given in entry NP_076950.1 (GeneID 79009).
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
DDX50
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Positive Control |
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Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
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| Buffer |
TBS and 0.1% BSA
|
| Preservative |
0.09% Sodium Azide
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| Concentration |
0.2 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for DDX50 Antibody
- ATP-dependent RNA helicase DDX50
- DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
- DEAD box protein 50
- EC 3.6.1
- EC 3.6.4.13
- GU2
- GUB
- gu-beta
- MGC3199
- Nucleolar protein Gu2
- RH-II/GuB
- RNA helicase II/Gu beta
Background
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing. This gene and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene duplication in evolution. This gene has pseudogenes on chromosomes 2, 3 and 4. Alternative splicing of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined.
