DLG5 Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to a region between residue 1325 and 1375 of human discs, large homolog 5 using the numbering given in entry NP_004738.3 (GeneID 9231).
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
DLG5
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
|
| Preservative |
0.09% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for DLG5 Antibody
- discs, large homolog 5 (Drosophila)
- KIAA0583large (Drosophila) homolog 5
- LP-DLG
Background
DLG5 (discs large homolog 5) is a member of the family of discs large (DLG) homologs, a subset of the membrane-associated guanylate kinase (MAGUK) superfamily. The MAGUK proteins are composed of a catalytically inactive guanylate kinase domain, in addition to PDZ and SH3 domains, and are thought to function as scaffolding molecules at sites of cell-cell contact. DLG5 localizes to the plasma membrane and cytoplasm, and interacts with components of adherens junctions and the cytoskeleton. It is proposed to function in the transmission of extracellular signals to the cytoskeleton and in the maintenance of epithelial cell structure. [from NCBI GeneID:9231]
