E4F1 Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to a region between residue 725 and the C-terminus (residue 784) of human E4F1 (p120E4F) using the numbering given in entry NP_004415.1 (GeneID 1877).
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| Predicted Species |
Mouse (100%), Rat (100%), Porcine (100%), Bat (100%), Primate (100%), Bovine (100%), Equine (100%), Canine (100%), Rabbit (100%). Backed by our 100% Guarantee.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
E4F1
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Human. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine, Dog, Horse, Rabbit, Pig, Panda, Orangutan, Gorilla, Chimpanzee, White-tufted-ear marmoset, Little brown bat, Northern white-cheeked gibbon, and Red-chested mustached tamarin.
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
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| Preservative |
0.09% Sodium Azide
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| Concentration |
1.0 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for E4F1 Antibody
- E4F transcription factor 1p50E4F
- E4FMGC99614
- EC 6.3.2.-
- p120E4F
- Putative E3 ubiquitin-protein ligase E4F1
- Transcription factor E4F
- transcription factor E4F1
Background
The zinc finger protein encoded by this gene is one of several cellular transcription factors whose DNA-binding activities are regulated through the action of adenovirus E1A. A 50-kDa amino-terminal product is generated from the full-length protein through proteolytic cleavage. The protein is differentially regulated by E1A-induced phosphorylation. The full-length gene product represses transcription from the E4 promoter in the absence of E1A, while the 50-kDa form acts as a transcriptional activator in its presence.
