EME1 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human EME1. The exact sequence is proprietary.
|
| Localization |
Nucleus; nucleolus
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
EME1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
63 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for EME1 Antibody
- crossover junction endonuclease EME1
- EC 3.1.22
- EC 3.1.22.-
- essential meiotic endonuclease 1 homolog 1 (S. pombe)
- essential meiotic endonuclease 1 homolog 2
- FLJ31364
- hMMS4
- homolog of yeast EME1 endonuclease
- MMS4 homolog
- MMS4
- MMS4L
- SLX2 structure-specific endonuclease subunit homolog A
- SLX2A
Background
EME1 and MUS81 (MIM 606591) form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication (Abraham et al., 2003 [PubMed 14609959]).[supplied by OMIM]
