EMR3 Antibody Summary
| Immunogen |
Synthetic 19 amino acid peptide from N-terminal extracellular domain of human EMR3.
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| Specificity |
Human EMR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
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| Predicted Species |
Primate (100%). Backed by our 100% Guarantee.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
EMR3
|
| Purity |
Immunogen affinity purified
|
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Orangutan (100%), Gibbon (100%), Bovine (89%).
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
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| Preservative |
0.1% Sodium Azide
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| Concentration |
1.0 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for EMR3 Antibody
- egf-like module containing, mucin-like, hormone receptor-like 3
- EGF-like module receptor 3
- EGF-like module-containing mucin-like hormone receptor-like 3
- egf-like module-containing mucin-like receptor 3
- EMR3
Background
EMR3 is an Orphan-B GPCR with an unknown ligand. Two variants are produced by alternative splicing. One form encodes a 652-amino acid GPCR consisting of two EGF-like domains and a mucin stalk, while the other is a truncated soluble form containing only two EGF-like domains. EMR3 and EMR2 share a high degree of sequence identity in the transmembrane domains. EMR3 has been reported to be expressed in neutrophils, monocytes, and macrophages. ESTs have been isolated from liver/spleen and mixed libraries.
