Gelsolin/GSN Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human Gelsolin. The exact sequence is proprietary.
|
| Localization |
Isoform 2: Cytoplasm; cytoskeleton; Isoform 1: Secreted
|
| Predicted Species |
Mouse (95%), Rat (95%), Sheep (96%), Bovine (96%). Backed by our 100% Guarantee.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
GSN
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
86 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Chicken (81%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Gelsolin/GSN Antibody
- Actin-depolymerizing factor
- ADF
- AGEL
- Brevin
- DKFZp313L0718
- gelsolin (amyloidosis, Finnish type)
- Gelsolin
- GSN
Background
The protein encoded by this gene binds to the “plus” ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq]
