Hexokinase 2 Antibody (1A7) Summary
| Immunogen |
Recombinant human Hexokinase 2 (1-917aa) purified from E. coli
|
| Specificity |
Anti-human Hexokinase 2 mAb, clone 1A7, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Hexokinase 2 protein.
|
| Isotype |
IgG1
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
HK2
|
| Purity |
Protein G purified
|
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|
Applications/Dilutions
| Dilutions |
|
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4) and 10% Glycerol
|
| Preservative |
0.02% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Protein G purified
|
Alternate Names for Hexokinase 2 Antibody (1A7)
- DKFZp686M1669
- EC 2.7.1
- Hexokinase 2
- Hexokinase type II
- HK2
- HKII
- HXK2
- Muscle form hexokinase
- muscle
Background
Hexokinase is the first enzyme in the glycolytic pathway, catalyzing the transfer of a phosphoryl group from ATP to glucose to form glucose-6-phosphate and ADP. In mammals, four distinct enzymes (types 1 to 4 hexokinases) have been identified. These enzymes are found in most cells, but there is tissue specificity for the particular type of hexokinase. Hexokinase 2 is found in the skeletal muscle and includes hydrophobic N-terminal sequence capable of targeting the hexokinase to mitochondria.
