IBTK Antibody Summary
| Immunogen |
IBTK (NP_056340, 1 a.a. ~ 1353 a.a) full-length human protein.MSSPMPDCTSKCRSLKHALDVLSVVTKGSENQIKAFLSSHCYNAATIKDVFGRNALHLVSSCGKKGVLDWLIQKGVDLLVKDKESGWTALHRSIFYGHIDCVWSLLKHGVSLYIQDKEGLSALDLVMKDRPTHVVFKNTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGL
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| Specificity |
IBTK – inhibitor of Bruton agammaglobulinemia tyrosine kinase,
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| Clonality |
Polyclonal
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| Host |
Mouse
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| Gene |
IBTK
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| Purity |
Protein A purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
Protein A purified
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Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for IBTK Antibody
- Bruton agammaglobulinemia tyrosine kinase inhibitor
- BTK-binding protein
- BTKI
- DKFZP564B116
- IBtk
- inhibitor of Bruton agammaglobulinemia tyrosine kinase
- inhibitor of Bruton tyrosine kinase
- inhibitor of Brutons tyrosine kinase
- inhibitor of Brutons tyrosine kinase-alpha
- inhibitor of Brutons tyrosine kinase-beta
- inhibitor of Brutons tyrosine kinase-gamma
- KIAA1417
- MGC142256
- MGC142258
- RP1-93K22.1
Background
The protein encoded by this gene binds to Brutons tyrosine kinase (BTK) and downregulates BTKs kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. [provided by RefSeq]
