Importin-8 Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to a region between residue 987 and 1037 of human RAN binding protein 8 using the numbering given in entry NP_006381.2 (GeneID 10526).
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| Predicted Species |
Monkey (100%), Primate (100%). Backed by our 100% Guarantee.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
IPO8
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Human. Based on 100% sequence identity, this antibody is predicted to react with Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear marmoset and Crab-eating macaque
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
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| Preservative |
0.09% Sodium Azide
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| Concentration |
1.0 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for Importin-8 Antibody
- FLJ21954
- FLJ26580
- Imp8
- importin 8
- importin-8
- RAN binding protein 8
- Ran-binding protein 8
- RanBP8
- RANBP8imp8
Background
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. [provided by RefSeq]
