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Product: 2-Cl-IB-MECA

KOR Antibody Summary

Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Kappa Opioid Receptor. The exact sequence is proprietary.
Localization
Cell membrane; Multi-pass membrane protein
Predicted Species
Rat (93%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
OPRK1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
43 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Mouse (86%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.91 mg/ml
Purity
Immunogen affinity purified

Alternate Names for KOR Antibody

  • kappa opioid receptor
  • kappa-type opioid receptor
  • KOR
  • K-OR-1
  • KOR-1
  • Opiate receptor, kappa-1
  • opioid receptor, kappa 1
  • OPRK
  • OPRK1
  • Oprk2
  • R21

Background

Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for dynorphins. May play a role in arousal and regulation of autonomic and neuroendocrine functions.

PMID: 3814920

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Author: premierroofingandsidinginc

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Product: Delavirdine (mesylate)

KOR Antibody Summary

Immunogen
Synthetic 19 amino acid peptide from 2nd extracellular domain of human Kappa Opioid Receptor.
Specificity
Human Kappa Opioid Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Mouse (95%), Rat (95%), Guinea Pig (95%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
OPRK1
Purity
Immunogen affinity purified
Innovators Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Learn about the Innovators Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 2.5 ug/ ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (100%), Marmoset (100%), Gorilla (95%), Elephant (95%), Bat (89%), Bovine (89%), Panda (89%), Opossum (84%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for KOR Antibody

  • kappa opioid receptor
  • kappa-type opioid receptor
  • KOR
  • K-OR-1
  • KOR-1
  • Opiate receptor, kappa-1
  • opioid receptor, kappa 1
  • OPRK
  • OPRK1
  • Oprk2
  • R21

Background

KOR1, an Opioid Receptor, plays a modulatory role in specific aspects of opioid function such as the control of pain. Its endogenous ligand, dynorphin A, is an important neurotransmitter in the central and peripheral nervous systems. KOR1 is believed to mediate sedation, analgesia, and diuresis.KOR1 has been reported to be expressed in the central and peripheral nervous systems, placenta, uterus, breast, and blood. ESTs have been isolated from placenta and prostate libraries.

PMID: 21844187

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Author: premierroofingandsidinginc