Product: Olcegepant (hydrochloride)
Kallikrein 5 Antibody Summary
| Immunogen |
Peptide with sequence KAGRDSCQGD corresponding to internal region according to NP_036559.1.
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| Epitope |
KAGRDSCQGD
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| Specificity |
Reported variants represent identical protein (NP_036559.1; NP_001070959.1; NP_001070960.1).
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
KLK5
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Approx. 37 kDa band observed in human prostate lysates (calculated MW of 32.0 kDa band according to NP_036559.1).
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| Positive Control |
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| Publications |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Rat, Canine, Bovine.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
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| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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| Preservative |
0.02% Sodium Azide
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| Concentration |
0.5 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for Kallikrein 5 Antibody
- EC 3.4.21
- EC 3.4.21.4
- Kallikrein 5
- Kallikrein-like protein 2
- kallikrein-related peptidase 5
- KLK5
- KLKL2
- KLK-L2
- KLK-L2EC 3.4.21.-
- SCTE
- SCTEkallikrein-5
- Stratum corneum tryptic enzyme
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.
