Kallikrein 7 Antibody Summary
| Immunogen |
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Kallikrein 7. The exact sequence is proprietary.
|
| Localization |
Secreted
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
KLK7
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Theoretical MW |
28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.31 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Kallikrein 7 Antibody
- EC 3.4.21
- EC 3.4.21.117
- hK7
- hSCCE
- kallikrein 7 (chymotryptic, stratum corneum)
- Kallikrein 7
- kallikrein-related peptidase 7
- KLK7
- protease, serine, 6
- PRSS6
- SCCEkallikrein-7
- Serine protease 6
- signal protein
- Stratum corneum chymotryptic enzyme
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded enzyme is thought to be involved in the proteolysis of intercellular cohesive structures preceding desquamation, which is the shedding of the outermost layer of the epidermis. Alternative splicing of this gene results in two transcript variants encoding the same protein.
