Product: NADPH (tetracyclohexanamine)
LGTN Antibody Summary
Immunogen |
The immunogen for this product maps to a region between residue 350 and 400 of human eIF2D using the numbering given in entry NP_008824.2 (GeneID 1939).
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Predicted Species |
Canine (100%), Equine (100%), Bovine (100%), Primate (100%), Bat (100%). Backed by our 100% Guarantee.
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Clonality |
Polyclonal
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Host |
Rabbit
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Gene |
EIF2D
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Purity |
Immunogen affinity purified
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Innovators Reward |
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Applications/Dilutions
Dilutions |
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Reactivity Notes
Based on 100% sequence identity, this antibody is predicted to react with Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear marmoset, Crab-eating macaque, African elephant, Small-eared galago, Little brown bat and Northern white-cheeked gibbon.
Packaging, Storage & Formulations
Storage |
Store at 4C. Do not freeze.
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Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
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Preservative |
0.09% Sodium Azide
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Concentration |
1 mg/ml
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Purity |
Immunogen affinity purified
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Alternate Names for LGTN Antibody
- eukaryotic translation initiation factor 2D
- HCA56eIF2d
- Hepatocellular carcinoma-associated antigen 56
- LGTNLigatin
- ligatin
Background
This gene encodes a protein receptor that localizes phosphoglycoproteins within endosomes and at the cell periphery. This trafficking receptor for phosphoglycoproteins may play a role in neuroplasticity by modulating cell-cell interactions, intracellular adhesion, and protein binding at membrane surfaces. In hippocampal neurons, long-lasting down-regulation of ligatin mRNA levels occurs via post-transcriptional RNA processing following glutamate receptor activation. This protein contains single PUA and SUI1 domains and these domains may function in RNA binding and translation initiation, respectively.