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Product: Etimizol

MAP1 Antibody Summary

Immunogen
MOAP1 (NP_071434, 1 a.a. ~ 351 a.a) full-length human protein.MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDENRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGELSRALGHENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPGEEEFGRWMFHTTQMIKAWQVPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEEVFGVTDNPRELQVKYL
Specificity
MOAP1 – modulator of apoptosis 1,
Clonality
Polyclonal
Host
Mouse
Gene
MOAP1
Purity
Unpurified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
Application Notes
Antibody reactive against Immunizing Recombinant Protein or Transfected Lysate on ELISA and Western Blot.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
Serum
Preservative
No Preservative
Purity
Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for MAP1 Antibody

  • MAP1
  • MAP-1PNMA4Paraneoplastic antigen Ma4
  • modulator of apoptosis 1
  • paraneoplastic antigen like 4

Background

The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis.

PMID: 8574653

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Author: premierroofingandsidinginc

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Product: Hydroxyhexamide

MAP1 Antibody Summary

Immunogen
Antibody was raised against a 15 amino acid synthetic peptide from near the center of human MAP-1. The immunogen is located within the last 50 amino acids of MAP1.
Clonality
Polyclonal
Host
Rabbit
Gene
MOAP1
Purity
Immunogen affinity purified
Innovators Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Learn about the Innovators Reward

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
Application Notes
MAP1 antibody can be used for the detection of MAP-1 by Western blot at 1 mg/ml.
Control Peptide
MAP1 Peptide (NBP1-76453PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for MAP1 Antibody

  • MAP1
  • MAP-1PNMA4Paraneoplastic antigen Ma4
  • modulator of apoptosis 1
  • paraneoplastic antigen like 4

Background

Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). Members of the Bcl-2 family are known to be critical regulators of this process. These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains. A related protein termed MAP-1 has recently been identified. This protein contains a BH3-like domain and induces caspase-dependent apoptosis in mammalian cells when overexpressed. It forms homodimers and associates with Bcl-2 family members such as Bax, Bcl-2, and Bcl-XL in vitro and in vivo. It has been suggested that MAP-1 associates with the tumor suppressor RASSF1A following death receptor activation, allowing a conformational change in Bax that leads to cellular apoptosis.

PMID: 16636137

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Author: premierroofingandsidinginc