Product: Angiotensin II 5-valine
MATK Antibody (9D7) Summary
| Immunogen |
Purified recombinant fragment of human MATK expressed in E. Coli.
|
| Isotype |
IgG1
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
MATK
|
| Purity |
Protein G purified
|
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|
Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS and 50% Glycerol
|
| Preservative |
0.03% Sodium Azide
|
| Purity |
Protein G purified
|
Alternate Names for MATK Antibody (9D7)
- CHK
- Csk-type protein tyrosine kinase
- CTKEC 2.7.10.2
- DKFZp434N1212
- EC 2.7.10
- Hematopoietic consensus tyrosine-lacking kinase
- HHYLTK
- hydroxyaryl-protein kinase
- HYL tyrosine kinase
- HYLCsk-homologous kinase
- HYLTK
- leukocyte carboxyl-terminal src kinase related
- Lsk
- megakaryocyte-associated tyrosine kinase
- megakaryocyte-associated tyrosine-protein kinase
- MGC1708
- MGC2101
- Protein kinase HYL
- tyrosine kinase MATK
- Tyrosine-protein kinase CTK
- tyrosylprotein kinase
Background
megakaryocyte-associated tyrosine kinase. The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.
