MCM3AP Antibody Summary
| Immunogen |
The immunogen for this product maps to a region between residue 1930 and 1980 of human Germinal center-Associated Nuclear Protein using the numbering given in entry NP_003897.2 (GeneID 8888).
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
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| Gene |
MCM3AP
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
|
| Preservative |
0.09% Sodium Azide
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for MCM3AP Antibody
- 80 kDa MCM3-associated protein
- FLJ44336
- GANPFLJ45306
- human mRNA for MCM3 import factor10Protein GANP
- KIAA0572MAP80germinal center-associated nuclear protein
- Map80
- MCM3 import protein
- MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) associated protein
- MCM3 minichromosome maintenance deficient 3 associated protein
- minichromosome maintenance complex component 3 associated protein
- minichromosome maintenance deficient (S. cerevisiae) 3-associated protein
- minichromosome maintenance deficient 3-associated protein
Background
The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization.
