MNX1/HLXB9 Antibody Summary
| Immunogen |
The immunogen for this product maps to a region between residue 351 and 401 of human MNX1/HLXB9 using the numbering given in entry NP_005506.3 (GeneID 3110).
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
MNX1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
|
| Preservative |
0.09% Sodium Azide
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for MNX1/HLXB9 Antibody
- HB9
- HLXB9motor neuron and pancreas homeobox protein 1
- homeobox HB9
- HOXHB9Homeobox protein HB9
- motor neuron and pancreas homeobox 1
- SCRA1homeo box HB9
Background
The homeobox gene Hb9/Hlxb9, is expressed selectively by motor neurons (MNs) in the developing vertebrate CNS. Hb9, which encodes a factor central to MN development regulates neuronal fate by restricting expression of Lim3 and Even-skipped (Eve), two homeodomain (HD) proteins required for development of distinct neuronal classes. In the vertebrate CNS, HB9/MNR2 transcription factors are specifically expressed in all somatic motoneurons and are necessary to distinguish motoneurons from interneurons. Hb9 is also a transcription factor expressed in lymphoid and pancreatic tissue. In humans, HB9 mutation causes an autosomal dominant form of sacral agenesis.
