MRCK Antibody Summary
| Immunogen |
The immunogen for this product maps to a region between residue 1560 and 1610 of human myotonic dystrophy protein kinase-like alpha using the numbering given in entry CAH71185.1 (GeneID 8476).
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| Clonality |
Polyclonal
|
| Host |
Rabbit
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| Gene |
CDC42BPA
|
| Purity |
Immunogen affinity purified
|
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Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
|
| Preservative |
0.09% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for MRCK Antibody
- CDC42 binding protein kinase alpha (DMPK-like)
- CDC42 binidng protein kinase beta
- CDC42-binding protein kinase alpha (DMPK-like)
- CDC42-binding protein kinase alpha
- DMPK-like alpha
- EC 2.7.11
- EC 2.7.11.1
- KIAA0451DKFZp686L1738
- MRCK alpha
- MRCK
- MRCKADKFZp686P1738
- Myotonic dystrophy kinase-related CDC42-binding kinase alpha
- myotonic dystrophy kinase-related CDC42-binding protein kinase alpha
- Myotonic dystrophy protein kinase-like alpha
- PK428FLJ23347
- serine/threonine-protein kinase MRCK alpha
- ser-thr protein kinase PK428
- ser-thr protein kinase related to the myotonic dystrophy protein kinase
Background
The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.
