Product: Migalastat (hydrochloride)
MYRIP Antibody Summary
| Immunogen |
Peptide with sequence C-KDLMEPALESAVMY corresponding to C-Terminus according to NP_056275.2.
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
MYRIP
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Approx. 90 kDa band observed in human brain (amygdala) lysates (calculated MW of 95.7 kDa band according to NP_056275.2).
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| Positive Control |
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
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| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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| Preservative |
0.02% Sodium Azide
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| Concentration |
0.5 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for MYRIP Antibody
- DKFZp586F1018
- exophilin-8
- FLJ44025
- MGC130034
- myosin VIIA and Rab interacting protein
- Myosin-VIIa- and Rab-interacting protein
- MyRIP
- rab effector MyRIP
- SLAC2-C
- SLAC2CMGC130035
- Slp homolog lacking C2 domains c
- Slp homologue lacking C2 domains
- synaptotagmin-like protein homologue lacking C2 domains-c
Background
A molecular complex composed of Rab27A, MYRIP and myosin VIIa bridges retinal melanosomes to the actin cytoskeleton and thereby mediates the local trafficking of these organelles. The defect of this molecular complex is likely to account for the perinuclear mislocalization of the melanosomes observed in the retinal pigment epithelium cells of myosin VIIa-defective mice.
