Melanocortin-3 R/MC3R Antibody Summary
| Immunogen |
Peptide with sequence SIQKTYLEGDFV-C corresponding to N-Terminus according to NP_063941.2.
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
MC3R
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Approx. 40 kDa band observed in human brain lysates (calculated MW of 40.1 kDa band according to NP_063941.2).
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
|
| Preservative |
0.02% Sodium Azide
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| Concentration |
0.5 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for Melanocortin-3 R/MC3R Antibody
- BMIQ9
- MC3
- MC3R
- MC3-R
- melanocortin 3 receptor
- melanocortin receptor 3
- Melanocortin-3 R
- Melanocortin3R
- Melanocortin-3R
- OB20
- Obesity quantitative trait locus
- OQTL
Background
Melanocortins are ligands for a subgroup of GPCRs positively coupled to Adenylate cylcases, termed as melanocortin receptors (MC1R, MC2R, MC3R, MC4R amd MC5R). These receptors are widely expressed at varied density throughout the body. The MC3R has been widely implicated in inflammation and is also implicated in a role in obesity and metabolism. MC3R KO mice exhibit reduced linear growth and lean mass and are hyperleptinemic and hyperinsulinemic.
