Monopolin Antibody Summary
| Immunogen |
Synthetic peptide corresponding to a portion of human Monopolin.
|
| Specificity |
Monopolin
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Western blot – Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.
|
Reactivity Notes
Reacts with the Monopolin protein from Saccharomyce cerevisiae.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
|
| Preservative |
0.02% Sodium Azide
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Background
A novel kinetochore associated protein, Mam1 (Monopolin), plays a key role in the mechanism of meiotic chromosome segregation. It controls kinetochore behavior in meiosis I and defines a functional basis by which sister kinetochores are directed toward the same pole in meiosis I.
