NLRP7 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human NLRP7. The exact sequence is proprietary.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
NLRP7
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
112 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Rhesus Monkey (87%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.76 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for NLRP7 Antibody
- CLR19.4
- MGC126471
- NACHT, leucine rich repeat and PYD containing 7
- NACHT, LRR and PYD containing protein 7
- NACHT, LRR and PYD domains-containing protein 7
- NALP7MGC126470
- NLR family, pyrin domain containing 7
- NOD12HYDM
- Nucleotide-binding oligomerization domain protein 12
- nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domaincontaining 7
- PAN7
- PYPAF3FLJ94610
- PYRIN-containing APAF1-like protein 3
Background
This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
