Share this post on:

Product: ONO-4061 (analog)

PA1 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 1 and 50 of human PTIP-associated 1 protein using the numbering given in entry NP_078792.1 (GeneID 79447).
Clonality
Polyclonal
Host
Rabbit
Gene
PAGR1
Purity
Immunogen affinity purified
Innovators Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Learn about the Innovators Reward

Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 1:10-1:500
Positive Control
PA1 Lysate (NBL1-08216)

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PA1 Antibody

  • chromosome 16 open reading frame 53
  • FLJ22459
  • GAS
  • glutamate-rich coactivator interacting with SRC1/NCOA1
  • MGC4606
  • PA1
  • PAXIP1-associated protein 1
  • PTIP-associated 1 protein
  • PTIP-associated protein 1

Background

C16ORF53 (PA1) is a component of a Set1-like multiprotein histone methyltransferase complex (Cho et al., 2007 [PubMed 17500065]).[supplied by OMIM]

PMID: 10611442

Share this post on:

Author: premierroofingandsidinginc

Share this post on:

Product: Labetalol (hydrochloride)

PA1 Antibody Summary

Immunogen
Antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human GAS. The immunogen is located within the last 50 amino acids of GAS.
Clonality
Polyclonal
Host
Rabbit
Gene
PAGR1
Purity
Immunogen affinity purified
Innovators Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Learn about the Innovators Reward

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
Control Peptide
PA1 Peptide (NBP1-76239PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PA1 Antibody

  • chromosome 16 open reading frame 53
  • FLJ22459
  • GAS
  • glutamate-rich coactivator interacting with SRC1/NCOA1
  • MGC4606
  • PA1
  • PAXIP1-associated protein 1
  • PTIP-associated 1 protein
  • PTIP-associated protein 1

Background

Steroid receptor co-activators (SRCs) were initially described as nuclear receptor transcription co-activators, but they have recently been determined to co-regulate transcription initiated by other transcription factors. GAS is a recently identified glutamate-rich protein that interacts with SRC1, but not GRIP1 or AIB1, the other two members of the SRC family. GAS can also interact with the alpha subunit of the estrogen receptor (ERalpha), but not other receptors such as the retinoic acid receptor a, suggesting the interaction between GAS and ERalpha is relatively specific. Depletion of GAS by RNA interference in MCF7 cells led to a decrease in the mRNA and protein levels of ER target genes such as pS2, c-Myc and cyclin D1, indicating the role of GAS in the regulation of ER target genes. GAS has also been found to associate with an SET1-like methyltransferase complex specific for H3K4 methylation, suggesting that GAS has multiple roles in transcriptional regulation.

PMID: 21177701

Share this post on:

Author: premierroofingandsidinginc