PA2G4/EBP1 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human EBP1. The exact sequence is proprietary.
|
| Localization |
Cytoplasm; Nucleus; nucleolus
|
| Predicted Species |
Mouse (99%), Rat (99%), Xenopus (92%), Primate (100%), Bovine (100%). Backed by our 100% Guarantee.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
PA2G4
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
44 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for PA2G4/EBP1 Antibody
- Cell cycle protein p38-2G4 homolog
- EBP1
- ErbB-3 binding protein 1
- ErbB3-binding protein 1
- ErbB3-binding protein Ebp1
- HG4-1
- p38-2G4
- PA2G4
- proliferation-associated 2G4, 38kD
- proliferation-associated 2G4, 38kDa
- proliferation-associated protein 2G4
Background
This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. [provided by RefSeq]
