Product: Amiselimod (hydrochloride)
PAK4 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human PAK4. The exact sequence is proprietary.
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| Predicted Species |
Mouse (98%), Rat (98%), Zebrafish (94%), Bovine (99%). Backed by our 100% Guarantee.
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| Isotype |
IgG
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
PAK4
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| Purity |
Immunogen affinity purified
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| Innovators Reward |
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Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
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|
| Theoretical MW |
64 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
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| Preservative |
0.01% Thimerosal
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| Concentration |
1 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for PAK4 Antibody
- EC 2.7.11
- EC 2.7.11.1
- KIAA1142
- p21 protein (Cdc42/Rac)-activated kinase 4
- p21(CDKN1A)-activated kinase 4
- p21-activated kinase 4
- PAK4
- PAK-4
- protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs
- serine/threonine-protein kinase PAK 4
Background
PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]
