PBEF/Visfatin/NAMPT Antibody (4E11C9) Summary
| Immunogen |
Purified recombinant fragment of Visfatin expressed in E. Coli.
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
NAMPT
|
| Purity |
Unpurified
|
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|
Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
Ascites
|
| Preservative |
0.03% Sodium Azide
|
| Purity |
Unpurified
|
Alternate Names for PBEF/Visfatin/NAMPT Antibody (4E11C9)
- EC 2.4.2.12
- MGC117256
- NAmPRTase
- NAMPT
- nicotinamide phosphoribosyltransferase
- NMPRTase
- PBEF
- PBEF1
- PBEF1110035O14Rik
- PBEF1DKFZp666B131
- Pre-B cell-enhancing factor
- pre-B-cell colony enhancing factor 1
- Pre-B-cell colony-enhancing factor 1
- VF
- Visfatin
Background
PBEF1: nicotinamide phosphoribosyltransferase. This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
