PCCA Overexpression Lysate (Denatured) Summary
| Description |
Pasmid: pCMV-PCCA full-length
|
| Gene |
PCCA
|
Packaging, Storage & Formulations
| Storage |
Store at -80C. Avoid freeze-thaw cycles.
|
| Buffer |
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).
|
Lysate Details for PCCA
| Type |
Overexpression
|
| Protein State |
Denatured
|
Notes
Quality control test: Transient overexpression cell lysate was tested with Anti-PCCA antibody by Western Blots.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for PCCA Overexpression Lysate (Denatured)
- EC 6.4.1
- EC 6.4.1.3
- pccA complementation group
- PCCase alpha subunit
- PCCase subunit alpha
- propanoyl-CoA:carbon dioxide ligase alpha subunit
- Propanoyl-CoA:carbon dioxide ligase subunit alpha
- propionyl CoA carboxylase, alpha polypeptide
- propionyl Coenzyme A carboxylase, alpha polypeptide
- propionyl-CoA carboxylase alpha chain, mitochondrial
Background
The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
