PIMT Antibody Summary
| Immunogen |
C terminus of the human PIMT protein
|
| Specificity |
Reacts with the residues 839-853 of the C terminus of the human PIMT protein.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
TGS1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Western blot- Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| Theoretical MW |
117 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Human. Other species have not been tested.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
|
| Preservative |
0.02% Sodium Azide
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for PIMT Antibody
- Cap-specific guanine-N2 methyltransferase
- CLL-associated antigen KW-2
- DKFZp762A163
- EC 2.1.1
- EC 2.1.1.-
- HCA137
- Hepatocellular carcinoma-associated antigen 137
- NCOA6IPSEREX-defined
- nuclear receptor coactivator 6 interacting protein
- Nuclear receptor coactivator 6-interacting protein
- PIMTFLJ22995
- PIPMT
- PRIP-interacting protein PIPMT
- PRIP-interacting protein with methyltransferase domain
- PRIP-interacting protein with methyltransferase motif
- trimethylguanosine synthase 1
- trimethylguanosine synthase homolog (S. cerevisiae)
- trimethylguanosine synthase homolog
- trimethylguanosine synthase
Background
The nuclear receptor coactivators participate in the transcriptional activation of specific genes by nuclear receptors. Using a coactivator peroxisome proliferator-activated receptor-interacting protein (PRIP) as bait, a novel, protein has been identified, designated PRIP-interacting protein with methyltransferase domain (PIMT). It is expressed in heart, skeletal muscle, kidney, liver, and placenta and is a component of nuclear receptor signal transduction apparatus acting through PRIP.
