Product: Impurity of Doxercalciferol
RAD52 Antibody (5H9) Summary
| Immunogen |
Human Rad52 recombinant protein expressed in E. coli.
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| Specificity |
This antibody will recognize human Rad52.
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| Isotype |
IgG1
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| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
RAD52
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.2)
|
| Preservative |
No Preservative
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for RAD52 Antibody (5H9)
- DNA repair protein RAD52 homolog
- RAD52 (S. cerevisiae) homolog
- RAD52 homolog (S. cerevisiae)
- recombination protein RAD52
- rhabdomyosarcoma antigen MU-RMS-40.23
Background
DNA double-strand breaks can be generated by exposure to ionizing radiation or through endogenous cellular reactions. Double-strand breaks are generally thought to be repaired via one of two distinct mechanisms: homologous recombination (HR) or non-homologous end joining (NHEJ). Homologous recombination requires the activity of the members of the RAD52 epistasis group, which includeRAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2. RAD52 can catalyze strand annealing reactions, and can form oligomers that attach to ends of single-stranded DNA.
