Product: Hydroxyzine (dihydrochloride)
REEP4 Antibody Summary
| Immunogen |
Antibody was raised against a 17 amino acid synthetic peptide near the center of human REEP4. The immunogen is located within amino acids 160 – 210 of REEP4.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
REEP4
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Control Peptide |
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Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
PBS
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| Preservative |
0.02% Sodium Azide
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| Concentration |
1 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for REEP4 Antibody
- C8orf20chromosome 8 open reading frame 20
- FLJ22246
- FLJ22277
- PP432
- receptor accessory protein 4
- receptor expression enhancing protein 4
- receptor expression-enhancing protein 4
Background
Mammalian odorant receptors require accessory proteins such as RTP1 and RTP2 for functional cell surface expression. Receptor expression-enhancing protein (REEP) family members are transmembrane proteins which interact with odorant receptor proteins and may enhance the odorant receptor responses to odorants. Recently studies have shown other chemosensory receptors such as bitter taste receptors are also influenced by RTP and REEP family members. In studies in Xenopus RNAi to reduce REEP4 levels, embryos showed a slightly kinked body axis and were paralyzed. Further analysis revealed downregulated levels of several neural and muscle markers, suggesting the REEP4 may play a role in the maintenance of both the nervous system and musculature.
