ROBO1 Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to a region between residue 1275 and 1325 of human roundabout, axon guidance receptor, homolog 1 using the numbering given in entry NP_002932.1 (GeneID 6091).
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| Predicted Species |
Rat (100%), Bat (100%), Ferret (100%), Primate (100%), Canine (100%), Rabbit (100%). Backed by our 100% Guarantee.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
ROBO1
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Human. Based on 100% sequence identity, this antibody is predicted to react with Dog, Rabbit, Orangutan, Gorilla, Chimpanzee, White-tufted-ear marmoset, Naked mole rat, African elephant, European domestic ferret, and Little brown bat.
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
TBS and 0.1% BSA
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| Preservative |
0.09% Sodium Azide
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| Concentration |
0.2 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for ROBO1 Antibody
- DUTT1
- DUTT1Drosophila) homolog 1
- H-Robo-1
- MGC131599
- MGC133277
- ROBO1
- roundabout, axon guidance receptor, homolog 1 (Drosophila)
Background
ROBO1 (Roundabout homolog 1) is the receptor for SLIT1 and SLIT2. SLIT1 and SLIT2 play a role in axonal guidance in the major forebrain by regulating axon crossing at the midline and specifying directional positioning of longitudinal axonal pathways. ROBO1 is widely expressed and may also be important to lung development. ROBO1 has been reported to have tumor suppressor activity and to be frequently inactivated in lung and breast cancers.
