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Product: Thyroxine sulfate

ROR gamma/RORC/NR1F3 Antibody Summary

Immunogen
Peptide with sequence CHLEYSPERGKAE corresponding to internal region according to NP_005051.2, NP_001001523.1.
Specificity
This antibody is expected to recognize both reported isoforms (NP_005051.2; NP_001001523.1).
Clonality
Polyclonal
Host
Goat
Gene
RORC
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 0.1-0.3 ug/ml
  • Peptide ELISA Detection limit 1:16000
Application Notes
WB: Approx. 55 kDa band observed in human colon lysates (calculated MW of 55.8 kDa band according to NP_001001523.1).
Publications
Read Publication using NBP1-72057.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Mouse, Canine, Bovine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ROR gamma/RORC/NR1F3 Antibody

  • MGC129539
  • NR1F3
  • Nuclear receptor ROR gamma
  • Nuclear receptor ROR-gamma
  • Nuclear receptor RZR gamma
  • Nuclear receptor RZR-gamma
  • Nuclear receptor subfamily 1 group F member 3
  • RAR-Related Orphan Nuclear Receptor Variant 2
  • RAR-related orphan receptor C
  • RAR-related orphan receptor gamma
  • retinoic acid-binding receptor gamma
  • retinoid-related orphan receptor gamma
  • Retinoid-related orphan receptor-gamma
  • ROR gamma
  • RORC
  • RORG
  • RORGMGC129539
  • RZRG
  • RZRGRZR-GAMMA
  • TOR

PMID: 18407463

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Author: premierroofingandsidinginc

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Product: Arginase inhibitor 1

ROR gamma/RORC/NR1F3 Antibody Summary

Immunogen
Synthetic 19 amino acid peptide from ligand-binding domain of human ROR Gamma.
Epitope
ligand-binding domain of human
Specificity
Human ROR Gamma. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Mouse (95%), Rat (95%), Bat (95%), Hamster (95%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
RORC
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1:10 – 1:500

Reactivity Notes

Chimpanzee, Gorilla, Orangutan, Gibbon, Marmoset, Tamarin. Predicted cross-reactivity based on sequence identity: Elephant (100%), Panda (95%), Bovine (89%), Canine (89%), Rabbit (89%), Equine (89%), Opossum (89%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ROR gamma/RORC/NR1F3 Antibody

  • MGC129539
  • NR1F3
  • Nuclear receptor ROR gamma
  • Nuclear receptor ROR-gamma
  • Nuclear receptor RZR gamma
  • Nuclear receptor RZR-gamma
  • Nuclear receptor subfamily 1 group F member 3
  • RAR-Related Orphan Nuclear Receptor Variant 2
  • RAR-related orphan receptor C
  • RAR-related orphan receptor gamma
  • retinoic acid-binding receptor gamma
  • retinoid-related orphan receptor gamma
  • Retinoid-related orphan receptor-gamma
  • ROR gamma
  • RORC
  • RORG
  • RORGMGC129539
  • RZRG
  • RZRGRZR-GAMMA
  • TOR

Background

ROR gamma, a NR1 Thyroid Hormone-Like receptor, has been shown to affect thymopoiesis, bone metabolism, T-cell apoptosis, and lymphoid organogenesis. ROR gamma has been shown to promote thymocyte survival by activating the expression of the antiapoptotic protein Bcl-x(L). ROR gamma is also required for the development of lymph nodes and Peyers patches. It has been shown that ROR gamma t, a thymus-specific isoform of ROR gamma from mouse, inhibits Fas ligand expression and cytokine secretion in immature thymocytes. ROR gamma binds as a monomer to response elements composed of a single core motif, GGTCA, preceded by a 6 bp AT-rich sequence. ROR gamma expression has been documented in mouse thymus, adipose, bone, skeletal muscle, liver, and kidney, and in human skeletal muscle. ESTs have been isolated from human tissue libraries, including cancerous head/neck, germ cell, and prostate, and normal colon, head/neck, lung, liver/spleen, and pancreas.

PMID: 9419378

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Author: premierroofingandsidinginc